Electrochemical Detection of Levo-Tetrahydropalmatine Based on DNA Modified Electrode

DNA was employed in a novel way to contribute to the electroanalysis. Electrochemical oxidized DNA modified glassy carbon electrode (DNA/GCE) by potentiostatic method for Levotetrahydropalmatine (L-THP) determination was prepared. For the first time, L-THP was investigated by electrochemical sensor, and the results indicated that this voltammetric sensor exhibited a special recognition capacity towards L-THP determination. Under the optimize condition, the response peak currents had a linear relationship with the L-THP concentrations in range from 5.6×10 -5 mol L -1 to 2.8×10 -3 molL -1 with detection limit of 2.×10 -6 moi . L -1 .