Permselective and transparent wooden membrane with artemisinin-imprinted nanocages based on a MOFs@C3N4 self-assembly design

Molecularly imprinted membranes have superior selective separation capacity, rebinding capacity, and flux due to their microporous substrates and tightly packed molecularly imprinted polymers . In current study, artemisinin (Ars), the most effective antimalarial drug , is used as template molecule. The permeation-selectivity wooden membranes based on Ars-imprinted nanocages designed by metal organic framework@carbon nitride self-assembly process (MDWMs) has been successfully prepared: (i) based on three-dimensional mesoporous basswood membranes, dopamine-based auto-polymerization process was developed on basswood to for harvest the first layer imprinting and secondary reaction platform. (ii) The two-dimensional sheet carbon nitride modified by metal-organic framework is stably loaded on the surface of the polydopamine-modified basswood membrane, providing a rich irregular point array structure for the formation of recognition sites. Based on elaborate designs and optimizations, selectivity , rebinding capabilities, and flux are enhanced on the developed MDWMs ( β Are/Ars  = 6.49, β Aru/Ars  = 4.22, β DH-Ars/Ars  = 7.42), and high regeneration rate (>94% after 10 cycles) indicates that MDWMs have superior selectivity and stability. The MDWMs and preparation strategies developed here will provide a completely new design methodology for subsequent selective separation of Ars.