Hollow Spherical NiCo2O4 and Gold Nanoparticle Composite for Electrochemical Non-Enzymatic Glucose and H2O2 Sensing

A novel electrochemical non-enzymatic sensor for glucose and H2O2 based on metal organic framework (MOF)-derived cobalt-nickel bimetallic oxides (NiCo2O4) and gold nanoparticle (AuNPs) composite modified glassy carbon electrode (GCE) was fabricated in this paper. The structure and morphology of the prepared materials was successfully characterised by X-ray diffraction (XRD), element mapping images and scanning electron microscopy (SEM). Moreover, the electrocatalytic activity for glucose and H2O2 was investigated at the NiCo2O4/AuNPs/GCE using cyclic voltammetry (CV) and amperometric i–t technique. The catalytic currents for glucose and H2O2 are proportional to their concentrations in the range of 0.2 μM–581 μM and 0.5 μM–1774.5 μM, respectively. The corresponding limits of detection (LOD) were calcuated be 0.0081 μM and 0.181 μM for glucose and H2O2. Furthermore, the NiCo2O4/AuNPs/GCE shows excellent stability, reproducibility and anti-interference ability.