An abiotic carbon dots@ ZIF-90 fluorescent probe for rapid and reliable detection of adenosine triphosphate

ATP is a high-energy compound that plays a vital role in biological metabolism. Abnormal changes in ATP concentration are related to various diseases and reflect microbial metabolism in biofilms. In this work, we prepared carbon quantum dots (CDs) with aggregation-induced fluorescence inhibition effect using the bacterial culture medium as raw material with a hydrothermal method . Then, an abiotic fluorescent nanoprobe named [email protected] imidazolate frameworks-90 (ZIF-90) was facilely synthesized by encapsulating CDs into ZIF-90. Owing to the encapsulation of CDs in the hollow structure of ZIF-90, the blue fluorescence emission of [email protected] decreased significantly. In the presence of ATP, the ZIF-90 framework was destroyed due to the strong coordination between ATP and Zn 2+ . The released CDs exhibited stronger fluorescence intensity , which was closely related to the ATP concentration. The convenient synthesis process and rapid ATP-responsive ability make [email protected] highly promising for clinical and environmental analysis .