Resveratrol-Loaded Diacetate Fiber by Supercritical CO2 Fluid Assisted Impregnation

(1) Background: Supercritical CO2fluid (SCF-CO2)-assisted impregnation presents advantages on loading active drugs to polymer substrates, since it enables the realization of a drug-loaded polymer without any solvent residue. Besides, CO2gas and drugs can be recycled and utilized again. Resveratrol-loaded diacetate fiber by SCF-CO2-assisted impregnation was done to give diacetate fiber biological activity function for enhancing its added value. (2) Methods: The effect of SCF-CO2temperature, pressure and treatment time on loading ability (LA) of resveratrol onto diacetate fiber was explored by ultraviolet visible spectrophotometer. The variation of structure and property of diacetate fiber was analyzed by characterization instruments. (3) Results: LA had been increasing with SCF-CO2treatment time, temperature and pressure when SCF-CO2was above 70 °C, 12 MPa. The inhibiting rate of resveratrol to free radicals was affected positively by SCF-CO2. After resveratrol was impregnated by SCF-CO2it appeared some small white granular substances on the surface of diacetate fiber. It had a good interaction between resveratrol and molecular chain of diacetate fiber. (4) Conclusions: Resveratrol was well-loaded onto the diacetate fiber by SCF-CO2assisted impregnation.Keywords:diacetate fiber;supercritical CO2fluid;resveratrol;loading ability