High sensitivity electrochemiluminescence sensor based on the synergy of ZIF-7 and CdTe for determination of glucose

An electrochemical luminescence (ECL) sensor for the detection of glucose was constructed by covering CdTe nanomaterials, ZIF-7 and glucose oxidase (GOD) on the electrode surface, respectively. CdTe and ZIF-7, as co-reaction promoters, could amplify ECL signals through synergy effect. The results demonstrated that ECL intensity increased when the concentration of glucose increased. Based on the change of ECL intensity, a method for the determination of glucose was established. Possible response mechanisms were also studied. The parameters of measurement conditions were optimized. The linear range of glucose was 2.0 × 10 −10  ∼ 2.0 × 10 −5  mol L −1 and the detection limit was 6.7 × 10 −11  mol L −1 under the optimal conditions. The constructed sensor had high sensitivity and selectivity. The results were satisfactory for the determination of glucose in real human serum samples.