Ultrasensitive luteolin electrochemical sensor based on zeolitic imidazolate frameworks-derived cobalt trioxide @ nitrogen doped carbon nanotube/amino-functionalized graphene quantum dots composites modified glass carbon electrode

The accurate determination of luteolin is of great significance for food and pharmaceutical industry . Herein, an ultrasensitive electrochemical sensor for luteolin based on zeolitic imidazolate frameworks (ZIF)-derived cobalt trioxide @ nitrogen doped carbon nanotube/amino-functionalized graphene quantum dots composites modified glass carbon electrode (Co 3 O 4 @N-CNTs/NH 2 -GQDs/GCE) was constructed. The Co 3 O 4 @N-CNTs composites were synthesized through direct pyrolysis of ZIF-67 in the N 2 atmosphere, which exhibited outstanding electrochemical performance for luteolin due to the conductivity of N-CNTs and the catalytic action of Co 3 O 4 . Under optimized conditions, the Co 3 O 4 @N-CNTs /NH 2 -GQDs/GCE exhibited a linear range of 0.5–1000 nM for detecting luteolin, with a low detection limit (LOD) of 0.1 nM (S/N = 3). Furthermore, the sensor was successfully applied for the detection of luteolin in Chrysanthemum extracts.