The construction of CoP nanoparticles coated with carbon layers derived from core-shell bimetallic MOF for electrochemical detection of dopamine

Design of catalysts with unique structures in enhancing electrochemical activity and stability has still been pursued. An eco-friendly method for preparing CoP with improved electrochemical performances was proposed in this work. A novel P-doped bimetallic [email protected] ( [email protected] ) was prepared as the precursor for constructing of [email protected] /NCS, in which CoP nanospheres coated with carbon layers ( [email protected] for short) were well-dispersed on N-doped carbon spheres (NCS for short). P was strategically pre-introduced into [email protected] for preparing of [email protected] through the selective phosphorylation on ZIF-8 shell. DA was selected to investigate the electrochemical properties of [email protected] /NCS. Glassy carbon electrode (GCE) modified by [email protected] /NCS exhibited excellent properties in detection of DA by square wave stripping voltammetry (SWV), that a high sensitivity of 9.4 μA μM −1 , and low limit of detection of 0.03 μM. In addition, [email protected] /NCS showed enhanced performances on electrocatalytic oxidation of DA than that of CoP/C prepared based on ZIF-67 by the common phosphorization method reported in literatures. Moreover, a wide linear range from 5.0 μM to 400.0 μM was achieved at [email protected] /NCS/GCE by amperometric i-t. The practical application of CoP/NCS/GCE was evaluated by detection of DA in human serum. The satisfactory recoveries in diluted serum demonstrated the promising application of [email protected] /NCS.