Well-defined multifunctional superhydrophobic green nanofiber membrane based-polyurethane with inherent antifouling, antiadhesive and photothermal bactericidal properties and its application in bacteria, living cells and zebra fish

In recent years, the development of effective antibacterial surfaces and preventing ambient contamination are critically important for medical devices and public hygiene products. In this manuscript, we prepared a multifunctional nanofiber membrane ( PU–CNC–TiO 2 -CNFs-PDMS, PCTCP ) by integrating electrospinning technology and co-blending technique. It is shown that the superhydrophobic composite fiber membrane ( PCTCP ) was endowed with excellent mechanical properties , high elasticity, self-cleaning, anti-contamination, high leakage-proof ability and low cytotoxicity. Furthermore, photothermal and photodynamic behaviors made the fiber film have better bactericidal performance, which will provide additional benefit for medical applications. Hemolysis test demonstrated the ultra-low toxicity of composite fibrous membranes . Finally, the ultrahigh compatibility of fibrous membranes with L929 cells was confirmed by cell imaging using fluorescent confocal microscopy , and the co-culture of PCTCP with zebrafish further demonstrated the potential of fibrous membranes as biomedical materials .