Three-dimensional MoS2 nanoflowers supported Prussian blue and Au nanoparticles: A peroxidase-mimicking catalyst for the colorimetric detection of hydrogen peroxide and glucose

Well-dispersed Prussian blue (PB) and Au nanoparticles (Au NPs) loaded three dimensional MoS 2 nanoflowers (PB-Au@MoS 2 NFs) was synthesized by a simple and economical method. The structure, morphology and composition of the hybrid were characterized by XRD, SEM and EDS. Similar to the reported literature, MoS 2 nanoflowers showed peroxidase-like activity in catalyzing the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB). This peroxidase-mimicking activity could be enhanced with the introduction of PB and Au NPs. Herein, PB-Au@MoS 2 NFs could be used to establish a new platform for the determination of H 2 O 2 and glucose by the chromogenic reaction. Wide linear ranges with 0–15 μM and 0–120 μM for H 2 O 2 and glucose detection were finally obtained. The detection limits were as low as 0.25 μM and 3 μM (with signal to noise ratio of 3), respectively. The established platform was also used successfully for the determination of glucose in human serum and fruit juice samples with excellent sensitivity and stability.