Facile Synthesis of Reduced Graphene Oxide-octahedral Mn3O4 Nanocomposites as a Platform for the Electrochemical Determination of Metronidazole and Sulfamonomethoxine

A facile synthesis strategy of reduced graphene oxide (RGO)-octahedral Mn 3 O 4 (oct-Mn 3 O 4 ) nanocomposites using in situ one-pot hydrothermal reaction was reported. The RGO-oct-Mn 3 O 4 nanocomposites were drop-casted onto the surface of glassy carbon electrode (GCE) to obtain RGO-oct-Mn 3 O 4 /GCE. DPV results revealed that the performance of RGO-oct-Mn 3 O 4 /GCE towards metronidazole displayed a linear ranging from 0.1 to 9.5 μM with a detection limit of 0.037 μM. For sulfamonomethoxine, it exhibited a linear ranging from 1 to 95 μM with a detection limit of 0.27 μM. Moreover, the proposed sensor had good anti-interference capability, high stability, satisfactory reproducibility, and was successfully applied in real samples.