β-Cyclodextrin functionalized molybdenum disulfide quantum dots as nanoprobe for sensitive fluorescent detection of parathion-methyl

Through modifying molybdenum disulfide quantum dots (MoS 2 QDs) with 3-aminophenyl boronic acid and functionalizing further with hydropropyl-β-cyclodextrin (β-CD), a novel nanoprobe based on β-CD functionalized MoS 2 QDs (β-CD-MoS 2 QDs) was developed for the fluorescent detection of parathion-methyl (MP). β-CD-MoS 2 QDs was characterized with various technologies including transmission electron microscopy , X-ray photoelectron spectroscopy, fluorescence and UV–Vis absorption spectra. As for MP detection, MP was hydrolyzed to p-nitrophenol (p-NP) under the alkaline conditions, and p-NP can enter into the β-CD cavity due to the host-guest recognition capability of β-CD, which then results the fluorescence quenching of nanoprobe. Based on this principle, an enzyme-free fluorescence sensing platform were constructed for MP. Under the optimal conditions, β-CD-MoS 2 QDs nanoprobe exhibits wide detection scope (0.01–18.0 ppm) and low detection limits (3.3 ppb) for MP detection. In addition, the nanoprobe has excellent selectivity for MP, and it can be applied to detect MP in real samples.