Premixed tricalcium silicate/sodium phosphate dibasic cements for root canal filling

Mineral Trioxide Aggregate (MTA) showed good clinical outcomes for many endodontic diseases. However, poor handling characteristics and anti-washout ability of MTA largely limit its widespread applications. In this study, a premixed tricalcium silicate (TCS)/sodium phosphate dibasic (SPD) cement was developed to overcome the aforementioned disadvantages of MTA. The hardening mechanism of TCS/SPD premixed pastes was studied. The influences of SPD on washout resistance, injectability, flowablity, setting time and compressive strength of the premixed TCS pastes were investigated. Considering required radiopacity, ZrO 2 was incorporated, and radiopacity, anti-washout characteristics, bioactivity and sealability of radiopaque cements were studied. The results revealed that addition of SPD changed the phase compositions and morphologies of hydration products of cements. The anti-washout performance of TCS/SPD premixed cements was greatly enhanced due to improved cohesion of pastes. Additionally, TCS/SPD premixed pastes had good injectability and flowability . The setting time and compressive strength displayed a decreasing trend after adding SPD. The radiopacity of cements significantly increased from 1.54 to 3.64 mm Al with increasing ZrO 2 content from 0 to 30 wt%, and the radiopaque premixed pastes showed good apatite formation-ability and sealing property. These results indicated that radiopaque TCS/SPD premixed cements could be a novel promising dental cement .