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Fragment synthesis of disulfide-containing peptides

Journal 2020 · IF 0 · 发表于 2020 年 6 月 4 日
作者: Yuxuan Dai,Na Yue,Wenlong Huang,Hai Qian
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摘要

A new strategy for solid phase peptide synthesis in the fragment synthesis based on the use of 2-Cl-trityl resin as carrier to obtain protected peptide-resin and Rink Amide Resin, HOBT/HBTU or PyBOP/DIPEA or HATU/DIPEA as the coupling method is described. The highlights of this method are: • Simple. • Low cost. • Solid phase based.

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