Synthesis and characterizations of a series of water soluble polyamides and their micellization behavior

A series of water soluble polyamides were synthesized via melt-polycondensation using glutaric acid and poly(propylene glycol) bis(2-aminopropyl ether) as monomers . The chemical structures of the polyamides were ascertained by FT-IR and 1 H NMR. The thermal properties of the polyamides under consideration were measured by TGA and DSC . It was found that one kind of the polyamides can self-assemble into nano-size vesicles with densely packed multilayer wall in aqueous solution, while another polyamide can self-assemble into large complex micelles . Interestingly, these large complex micelles display a unique acid sensitive characteristic according to the TEM and PST measurements.