Preparation and characterization of hydroxyapatite macrobeads based on pneumatic extrusion dripping

Extrusion dripping is a facile method for the preparation of millimetre-size macrobeads. In this work, a pneumatic extrusion dripping system has been established to fabricate hydroxyapatite macrobeads with a controlled size. The size of the hydroxyapatite spherical beads could be tailored by adjusting the dripping parameters. This work is believed to provide an alternative method for the fabrication of hydroxyapatite macrobeads that can be used in bone regeneration.