Preparation and characterisation of poly(butylene succinate) microcarriers containing pesticide

Microcarriers containing pesticide have been designed to improve drug stability and increase release efficiency, which is favourable to the environment and agriculture development. In this work, biodegradable poly(butylene succinate) microspheres containing pesticide, λ-cyhalothrin, as an active agent are prepared by the solvent evaporation induced phase separation method. The microspheres show a uniform morphology and a narrow particle size distribution. The pesticide content is measured by high-performance liquid chromatography. The prepared microcarriers demonstrate high-loading capacity, encapsulation efficiency and long release time, which may find potential applications as new pesticide formulations.