Electrochemical detection of adenine and guanine using a three-dimensional WS2 nanosheet/graphite microfiber hybrid electrode

In this work, a WS 2 nanosheet/graphite microfiber hybrid electrode has been fabricated by in situ synthesis of WS 2 nanosheets on the surface of graphite microfibers. The WS 2 nanosheets possess an excellent electrocatalytic oxidation response towards adenine and guanine that encourages the adsorption of nucleobases and charge transfer at the surface of the microfibers. The WS 2 nanosheet/graphite microfiber hybrid electrode shows high sensitivity and selectivity for the detection of adenine and guanine. This hybrid microfiber electrode represents an excellent candidate platform for development of an electrochemical biosensor due to its low cost, flexibility and 3D morphology.