Macroscopic supramolecular assembly of rigid hydrogels assisted by a flexible spacing coating

To address the difficult challenge of realizing macroscopic supramolecular assembly (MSA) of high-modulus hydrogels, we propose a strategy of introducing a flexible spacing coating to improve the surface compliance for efficient MSA, which holds promise to develop versatile MSA methods for fabricating hydrogel-based tissue scaffolds, and to provide insight into the MSA mechanism.