Carbon nanotubes modified by a paramagnetic cationic surfactant for migration of DNA and proteins

We report the fabrication of magnetic carbon nanotubes (MCNTs) through one-step modification with a paramagnetic cationic surfactant for migration of DNA and proteins. DNA and proteins can effectively bind to the surfactant-coated MCNTs through electrostatic interaction. Targeted transport platform of DNA and proteins as delivery agents can be constructed upon application of an external magnetic field. The native conformation of these biomacromolecules can be suitably maintained without denaturation during the migration process. We expect it will find MCNTs potential applications in gene delivery, gene transfection, protein delivery and separation.