Electrospun bimetallic Au-Ag/Co3O4 nanofibers for sensitive detection of hydrogen peroxide released from human cancer cells

Bimetallic Au-Ag/Co 3 O 4 nanofibers (Au-Ag/Co 3 O 4 NFs) were synthesized by an electrospinning method and calcination treatment. Due to the admirable synergic effect of electrocatalytic ability of Au and Ag, and the large surface-to-volume ratio of Co 3 O 4 nanofibers caused by their rough surface, the synthesized Au-Ag/Co 3 O 4 NFs were applied to a sensing platform for hydrogen peroxide oxidation . Using electrochemical techniques, the novel sensing platform based on Au-Ag/Co 3 O 4 NFs shows a wide linear concentration range with high detection sensitivity of 1241.1 μA mM −1  cm −2 . This sensitive sensor was also applied to determine H 2 O 2 from human breast cancer cells, indicating its great potential application in physiology and pathology.