Ag nanoparticles-decorated nitrogen-fluorine co-doped monolayer MoS2 nanosheet for highly sensitive electrochemical sensing of organophosphorus pesticides

Two-dimensional (2D) MoS 2 shows great potential in the areas of electrochemical sensors due to their ultrathin structure and predominant physicochemical properties. However, pristine 2D MoS 2 nanostructure exists inherent disadvantages such as the limited electrical conductivity, surface area and easy aggregation or restacking. Here, nitrogen-fluorine co-doped monolayer 2D MoS 2 nanosheet decorated with Ag nanoparticles (Ag NPs-N-F-MoS 2 ) nanocomposite is prepared and it exhibits superior conductivity, remarkable electron mobility and high electroactive surface area. The obtained Ag NPs-N-F-MoS 2 are employed as a sensing platform for the electrochemical determination of organophosphate pesticide, coupled with enzymatic inhibition. Under optimized conditions, the acetylcholinesterase (AChE)/amino functionalized carbon nanotubes (CNTs-NH 2 )/Ag NPs-N-F-MoS 2 bioelectrode is superior in sensing performances for the detection of monocrotophos and chlorpyrifos, with wide linear ranges, low detection limit as low as 0.05 pg mL −1 (0.2 pM) and 1 pg mL −1 (3 pM) at a signal-to-noise ratio of 3, satisfactory selectivity, reproducibility and long-time storage stability. All results indicate that the Ag NPs-N-F-MoS 2 nanocomposite holds great promise for constructing an ultra-sensitive electrochemical sensing interface for the determination of pesticides.