A novel approach to 1,2,3-triazole grafted chitosans via modified Wolff’s cyclocondensation

A novel synthetic strategy to afford 1,2,3-triazole grafted chitosans via modified Wolff’s cyclocondensation was established. Subsequently, several multi-substituted 1,2,3-triazole grafted chitosans with a degree of conversion (DC) varying from 42.1% to 53.9% were synthesized and characterized. The chemical structures of the modified chitosans were confirmed by Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance spectroscopy ( 1 H NMR), and the DC of chitosan derivatives were determined by amino titration. Meanwhile, the impact of 1,2,3-triazole moieties in the chitosan on their thermal properties were characterized by thermogravimetic analysis (TGA) and differential calorimetry scanner (DSC) respectively.