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Metal-free protocol for the synthesis of N-arylpyrrolidines catalyzed by hydrogen iodine

Journal 2017 · IF 3.33 · 发表于 2017 年 2 月 24 日
作者: Tingting Hou,Chaofeng Zhang,Yehong Wang,Zhenting Liu,Zhixin Zhang,Feng Wang
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摘要

A metal-free and efficient approach to N -arylpyrrolidines from arylamines and cyclic ethers catalyzed by hydrogen iodine is described. In this protocol, no additive is added and a wide range of N -arylpyrrolidines are synthesized with up to 99% yield. Reaction mechanism involving iodine radical is proposed.

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