Monolithically integrated copper phosphide nanowire: An efficient electrocatalyst for sensitive and selective nonenzymatic glucose detection

The detection of glucose plays a significant role in diagnostics and management of diabetes and it is thus desired to develop non-noble-metal electrocatalyst for nonenzymatic glucose sensing. This work demonstrates the first use of monolithically integrated copper phosphide nanowire on copper foam (Cu 3 P NW/CF) as an efficient catalyst for electrochemical oxidation of glucose. As a nonenzymatic glucose sensor , this Cu 3 P NW/CF exhibits a low detection limit of 0.32   μM at a signal-to-noise ratio of 3 with a linear range from 0.005 to 1   mM (R 2   =   0.997). It also shows high anti-interference property to other normally co-existing electroactive species including lactose, fructose, ascorbic acid , uric acid , urea, dopiamine, and sucorse as well as excellent resistance to chloride poisoning. Its application for glucose detection in human serum sample is also demonstrated successfully.