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A pH-responsive asymmetric lipid vesicle as drug carrier

Journal 2016 · IF 1.631 · 发表于 2016 年 10 月 19 日
作者: Xunan Zhang,Wei Zong,Ying Hu,Nan Luo,Wenlong Cheng,Xiaojun Han
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摘要

In order to increase the loading efficiency of drug carriers, here we demonstrated a microfluidic method to fabricate an asymmetric vesicle, which contains trichloro(1H,1H,2H,2H-perfluoroocty-l)silane (TPS) inner leaflet and lipid outer leaflet. The asymmetric vesicle was characterised by fluorescence microscopy and Fourier transform infra-red spectrum. In vitro cytotoxicity of the vesicles carrying 5-fluorouacil (5-FU) has also been studied.

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