Flavonoids, Antioxidant Potential, and Acetylcholinesterase Inhibition Activity of the Extracts from the Gametophyte and Archegoniophore of Marchantia polymorpha L.

Marchantia polymorphaL. is a representative bryophyte used as a traditional Chinese medicinal herb for scald and pneumonia. The phytochemicals inM. polymorphaL. are terpenoids and flavonoids, among which especially the flavonoids show significant human health benefits. Many researches on the gametophyte ofM. polymorphaL.have been reported. However, as the reproductive organ ofM. polymorphaL., the bioactivity and flavonoids profile of the archegoniophore have not been reported, so in this work the flavonoid profiles, antioxidant and acetylcholinesterase inhibition activities of the extracts from the archegoniophore and gametophyte ofM. polymorphaL.were compared by radical scavenging assay methods (DPPH, ABTS, O2−), reducing power assay, acetylcholinesterase inhibition assay and LC-MS analysis. The results showed that the total flavonoids content in the archegoniophore was about 10-time higher than that of the gametophyte. Differences between the archegoniophore and gametophyte ofM. polymorphaL. were observed by LC-MS analysis. The archegoniophore extracts showed stronger bio-activities than those of the gametophyte. The archegoniophore extract showed a significant acetylcholinesterase inhibition, while the gametophyte extract hardly inhibited it.Keywords:Marchantia polymorphaL.;flavonoids;antioxidant potential;archegoniophore;gametophyte;acetylcholinesterase inhibition