Synergetic dual recognition and separation of the fungicide carbendazim by using magnetic nanoparticles carrying a molecularly imprinted polymer and immobilized β-cyclodextrin

The authors describe a nanomaterial for solid-phase extraction of carbendazim. Magnetic molecularly imprinted polymer nanoparticles (mag-MIP-NPs) were obtained by immobilizing the MIP and a thiolated β-cyclodextrin on the surface of magnetite (Fe 3 O 4 ) nanoparticles coated with gold nanoparticles. Both the recognition sites of the MIP and the hydrophobic cavities in the β-cyclodextrin contribute to the specific molecular recognition and extraction of carbendazim. The mag-MIP-NPs have an apparent adsorption capacity of 190 mg⋅g‾ 1 . Spiked vegetables were analyzed by using this material for extraction of carbendazim prior to its determination by ultra performance liquid chromatography (UHPLC). Recoveries range from 90.5 % to 109 %, and the detection limit is 3.0 pg⋅mL‾ 1 . Magnetic molecularly imprinted polymer nanoparticles (mag-MIP-NPs) were synthesized based on a thiolated β-cyclodextrin on the magnetic nanocomposite. Due to the synergetic dual recognition and separation effect, mag-MIP-NPs showed the good adsorption capacity of 190 mg⋅g‾ 1 for carbendazim.