Reduced graphene oxide-Hemin-Au nanohybrids: Facile one-pot synthesis and enhanced electrocatalytic activity towards the reduction of hydrogen peroxide

A facile and effective strategy is demonstrated for the synthesis of ternary reduced graphene oxide-Hemin-Au (rGO-H-Au) nanohybrids . The nanohybrids were synthesized through a one-pot in situ reduction of GO and HAuCl 4 under alkaline conditions using GO, Hemin and HAuCl 4 as the starting materials. The synthesis process can be finished within 1   h in a solution phase, without adding any additional surfactant, stabilizing agent and toxic or harsh chemical reducing agents. The resulting nanohybrids were characterized by UV–vis spectroscopy, Raman spectroscopy , transmission electron microscopy (TEM), and so on. Electrochemical measurements showed that the rGO-H-Au nanohybrids exhibited good electrocatalytic activity for the reduction of hydrogen peroxide (H 2 O 2 ). Based on this property, a simple and highly sensitive amperometric biosensor for H 2 O 2 had been developed. The linear relationships were obtained from 0.1   µM to 40   µM and the detection limit was estimated to be 30   nM. The simple and sensitive sensing platform showed great promising applications in the pharmaceutical, clinical and industrial detection of H 2 O 2 .