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Mitochondria-targeting phosphorescent iridium(III) complexes for living cell imaging

Journal 2014 · IF 4.097 · 43(44): 16872-16879 · 发表于 2014 年 9 月 15 日
作者: Qingqing Zhang,Rui Cao,Hao Fei,Ming Zhou
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摘要

Two phosphorescent iridium(III) complexes conjugated to a lipophilic triphenylphosphonium cation moiety, IrMitoOlivine and IrMitoNIR, were synthesized. The complexes show high mitochondria-specificity and relatively lower cytotoxicity. Time-lapse confocal imaging indicates that both complexes exhibit an excellent anti-photobleaching capability under continuous laser irradiation.

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