PtxNi/C nanostructured composites fabricated by chemical reduction and their application in non-enzymatic glucose sensors

Platinum–cobalt Pt x Ni alloy nanoparticles have been successfully fabricated by the chemical reduction method, using carbon (Vulcan XC-72) as support. The resulting modified glassy carbon electrode shows excellent catalytic activity for the oxidation of glucose. Under physiological conditions , the oxidation current of glucose has two specific linear ranges of 2.0   −   420   μM and 0.5–8.5   mM, with high sensitivities of 1795.1   μA   mM −1   cm −2 and 707.72   μA   mM −1   cm −2 , respectively. In addition, interference from the oxidation of ascorbic acid , uric acid , or acetamidophenol could be effectively avoided. The non-enzymatic glucose sensors based on this electrode exhibited excellent selectivity, stability, and repeatability. Thus, this novel non-enzyme sensor has potential application in glucose detection.