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KOH-Oriented Ring Openings of N-Tosylaziridines with Carboxylic Acids in DMSO

Journal 2014 · IF 0.873 · 52(1): 284-295 · 发表于 2014 年 5 月 12 日
作者: F. Zhang,H. Chang,W. Wei
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摘要

A facile and efficient KOH-oriented regioselective ring-opening reaction for the acetolysis of N -tosylaziridines in DMSO was developed under mild conditions. This operationally simple protocol could tolerate a variety of functionalized carboxylic acids as well as several N -tosylaziridines. Moreover, this strategy provided the corresponding ring-opening products with good results.

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