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Fabrication and characterization of porous HA/β-TCP scaffolds strengthened with micro-ribs structure

Journal 2012 · IF 2.307 · 发表于 2012 年 11 月 2 日
作者: Quan Wu,Xianglin Zhang,Bin Wu,Wei Huang
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摘要

The minimal demands for scaffolds include a guaranteed strength over time. In this study, a novel porous HA/β-TCP bioceramic scaffold with micro-ribs structure was fabricated by extrusion deposition technique and microwave sintering. Micro-ribs were placed at the center and corners of scaffold along the direction of load. Mechanical behaviors were studied to verify the strengthening effect of micro-ribs. Compared to the scaffold without micro-ribs, the average compressive strength of newly developed scaffold was remarkably improved from 28.3   MPa to 45.6   MPa under the porosity of 50%. Moreover, it also exhibited more stable and longer lasting mechanical strength during degradation in vitro. The effectiveness of micro-ribs on improving the mechanical performance of scaffolds provided a structural design reference for bone tissue engineering.

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