A new voltammetric sensor based on poly(L-arginine)/graphene–Nafion composite film modified electrode for sensitive determination of Terbutaline sulfate

A novel voltammetric sensor based on graphene–Nafion and poly( L -arginine) was constructed by electrodeposited and simple dipping–drying methods and used for high-sensitive determination of Terbutaline sulfate (TBS). The resulting poly( L -arginine)/graphene–Nafion modified electrode showed a significant voltammetric response to TBS due to the synergistic effect of poly( L -arginine) and graphene–Nafion, in which poly( L -arginine) had electrocatalytic ability for TBS and graphene provided a large specific surface area, excellent electric conductivity and electrocatalytic activity. The sensor gave a good linear range over 4.0   ×   10 −8 –5.0   ×   10 −6   mol   L −1 with a detection limit of 1.2   ×   10 −8   mol   L −1 towards the determination of TBS. The high sensitivity and selectivity together with the good linear relationship, very easy surface regeneration and good stability at such a modified electrode led us to construct a practical TBS biosensor successfully. This work promoted the potential applications of graphene-based materials in electrochemical sensors.