Simultaneous determination of iodide and iodate in povidone iodine solution by ion chromatography with homemade and exchange capacity controllable columns and column-switching technique

A simple ion chromatographic method for simultaneous detection of iodide and iodate in a single running was proposed, with columns packed with homemade functionalized polystyrene-divinylbenzene (PS-DVB) resins and column-switching technique. Homemade resins were functionalized with controllable amounts of quaternary ammonium groups. The low-capacity anion-exchange column and high-capacity anion-exchange column were prepared, due to the resins having different exchange capacities. With this method, iodide and iodate in povidone iodine solution were detected simultaneously in a short time with iodide being eluted off first. A series of standard solutions consisting of target anions of various concentrations from 0.01   mg/L to 100   mg/L were analyzed. Each anion exhibited satisfactory linearity, with correlation coefficient r   ≥   0.9990. The detection limits (LODs) for iodide and iodate obtained by injecting 100   μL of sample were 5.66 and 14.83   μg/L (S/N   =   3), respectively. A spiking study was performed with satisfactory recoveries between 101.2% and 100.6% for iodide and iodate.