Construction of electrochemical sensor of Cu2O-CuO-W3O-W2C composite material for rapid and sensitive detection of vanillic acid

Vanillic acid is a phenolic compound which has antioxidant properties and plays an essential role in the prevention of several degenerative diseases, including cancer and atherosclerosis. This work reports the development and application of a electrochemical sensor for vanillic acid detection by a composite material (Cu 2 O-CuO-W 3 O-W 2 C) using polyoxometal-based metal–organic frameworks (POMOFs) as precursor through thermal decomposition. The synthesized Cu 2 O-CuO-W 3 O-W 2 C have high electrical conductivity and excellent electrocatalytic performance. The electrochemical sensor displays a linear response between the current density and concentration of vanillic acid (50–1100 μM) with a lowest detection limit of 1.439 μM under optimal conditions. The sensor was also demonstrated for the determination of vanillic acid in different real samples (fruit juice and fruit peel) and satisfactory results were obtained.