Fully integrated wearable control system for micro/nanorobot navigation

Micro/nano robots have exhibited excellent application potential in the biomedical field, such as drug delivery, minimally invasive surgery, and bio-sensing. Furthermore, in order to achieve practical application, it is essential for swimming micro/nano robots to navigate towards specific targets or adjust their speed and morphology in complete environments. The navigation of swimming micro/nano robots with temporal and spatial precision is critical for fulfilling the demand of applications. Here, we introduced a fully integrated wearable control system for micro/nano robots navigation and manipulation, which is composed of a multifunctional sensor array, an artificial intelligence planner, and a magnetic field generator. The sensor array could perceive the real-time changes in gestures, wrist rotation, and acoustic signals. Artificial intelligence planner based on machine learning offers adaptive path planning in response to dynamically changing signals to generate magnetic fields for the on-demand manipulation of micro/nano robots. Such a novel, feasible control strategy was validated in the biological experiment in which cancer cells were targeted killed by photothermal therapy using micro/nano robots and integrated control platform. This wearable control system could play a crucial role in future intelligent medical applications and could be easily reconfigured toward other medical robots control.