MOF@Ag/AAB/Au@Ag composite matrix full-dimensional divergence effect-based SERS paper sensor for rapid carbaryl quantification

Carbaryl is a broad-spectrum carbamate fungicide that may pose a threat to ecosystems and human health. To prevent and control the harm caused by excessive application of carbaryl, a full-dimensional divergence effect SERS sensor has been constructed. Biodegradable paper chips were used as sensor substrates. ZIF-8 with structural flexibility was grown in situ on carbon paper. A rough silver layer with surface like metal etching was clad outside the ZIF-8. Artificial antibody (AAB) with accurate grasping ability was polymerized on the surface of ZIF-8@Ag paper substrate. Au@Ag CSNPs were decorated on the AAB to provide abundant “hot spots”. Every functional material layer works together to form a gap and tip region with superior plasmon resonance. The proposed SERS sensor realizes the rapid and accurate on-site screening and localization of carbaryl in food with good correlation responded in the range of 0.01–20 μg·mL −1 and a low detection limit of 5.72 × 10 –‍3 ‌ μ g·mL −1 .