Room-temperature synthesis of fluorinated covalent organic framework coupled with liquid chromatography-mass spectrometry for determination of per- and polyfluoroalkyl substances in drinking water

The routine monitoring of per- and polyfluoroalkyl substances (PFASs) in drinking water has become an important task in the field of public health. In this study, a fluorinated covalent organic framework (COF) was synthesized at room temperature using tetra-(4-aminophenyl) methane (TAM) and 2,3,5, 6-tetrafluoro-terephthalal (TFTA) as building blocks and named as TAM-TFTA-COF. The adsorption characteristics of PFASs on the TAM-TFTA-COF were investigated through adsorption model-fitting and molecular calculation. The TAM-TFTA-COF was served as the solid phase extraction (SPE) cartridge packing for the enrichment of PFASs. Combined with liquid chromatography–tandem mass spectrometry, the proposed method showed good linearity in the range of 1.25–375 ng·L −1 , low limits of detection (0.03–0.24 ng·L −1 ), and excellent intraday and interday precisions with RSD <10.3 %. Furthermore, this analytical method can be utilized for the determination of PFASs in tap water, spring water, and lake water with satisfactory accuracy.