Significant Enhanced Electrochemiluminescence Performance of 6-Methoxychromone/S2O82− System By 2-Naphthalene Sulfonic Acid as Co-reaction Accelerator and its Application

Graphical In this paper, We developed a novel ECL sensor of the 6-MC/S 2 O 8 2− system by using 2-NSA as co-reaction accelerator. 2-NSA was first proposed as co-reaction accelerator, promoting the generation of additional oxidant SO 4 − from S 2 O 8 2− , thus amplifying the ECL signal. Moreover, this research provides a highly sensitive platform for the detection of MV. In this paper, the novel ECL sensor of the 6-methoxychromone (6-MC)/S 2 O 8 2− system was designed by using 2-naphthalene sulfonic acid (2-NSA) as a co-reaction accelerator. Fluorescence, ECL spectrum, and cyclic voltammetry (CV) were used to explore extensively the ECL mechanism of the system. It is worth pointing out that 2-naphthalene sulfonic acid (2-NSA) was first proposed as a co-reaction accelerator, reacting with the coreactant K 2 S 2 O 8 rather than the luminophore, promoting the generation of additional oxidant SO 4 − from S 2 O 8 2− , thus amplifying the ECL signal. Furthermore, under the optimal experimental conditions, the high sensitivity of the 2-naphthalene sulfonic acid (2-NSA)+6-methoxychromone (6-MC)/S 2 O 8 2− system was realized for the detection of methyl violet (MV) in the linear range of 10 −8 ~10 −2 M, with a detection limit of 5.14×10 −10 M. In addition, this find offers some guidance for further developing co-reaction accelerators with excellent performance in the future.