High-performance non-enzyme glucose sensor based on 4-Iodopyridine-modified ZIF-67/MWCNT composite with enhanced conductivity and molecular permeability

ZIF-67-C 5 H 4 IN/MWCNT composites were successfully synthesized by doping 4-Iodopyridine (C 5 H 4 IN) and integrating multi-walled carbon nanotubes (MWCNT) IN cobalt dimethylimidazole (ZIF-67) via solvothermal and self-assembly methods. The composite was drop-cast on a glassy carbon electrode (GCE) for non-enzyme glucose detection IN alkaline media. The incorporation of C 5 H 4 IN modulated the three-dimensional metal-organic framework (MOF) structure of ZIF-67 and improved the molecular permeability, whereas the MWCNTs improved the electrical conductivity. As a result, the sensor offers excellent performance with a low limit of detection (LOD) of 0.78 μM, a linear range of 0.18–1.98 mM, and a sensitivity of 1033 μA mM −1  cm −2 . In addition, the sensor offers excellent stability, reproducibility and selectivity for common interferences.