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Real‐Time Monitoring of the Antiseizure Drug Valproic Acid Using a Novel Point‐Of‐Care Mass Spectrometry

Journal 2025 · IF 5 · 31(7): e70499 · 发表于 2025 年 7 月 3 日
作者: Xinqi Fang,Junhan Wu,Yuan Hong,Jiexun Bu,Wenpeng Zhang,Zheng Ouyang,Wei Hua,Ying Mao
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摘要

We present a novel point‐of‐care mass spectrometry system enabling rapid, real‐time quantification of valproic acid directly from whole blood. This bedside platform delivers serum‐equivalent results within 3 min and captures pharmacokinetic variability perioperatively, supporting individualized antiseizure therapy and timely clinical decision‐making in neurosurgical patients.

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