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Synthesis of carbon dots as an antibacterial and antioxidant agent

Journal 2025 · IF 4.2 · 发表于 2025 年 9 月 8 日
作者: Ying Zhang,Jie Wang,Xiuhong Wu,Rui Chang,Hongyu Luo,Juan Yang,Quan Wu,Ze Xu*,Yingfu Zhong
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摘要

Objective: A new type of antibacterial and antioxidant carbon dots has been discovered.Methods: In this study, a facile one-step hydrothermal method was employed to synthesize carbon dots (CDs) using Yongchuan Xiuya as the precursor.Results: The morphology and chemical composition of the synthesized CDs were systematically characterized. The resulting doped carbon quantum dots (CDs) exhibited a spherical shape with an average particle size of 4.17 nm and a lattice spacing of 0.22 nm. The CDs demonstrated exceptional antioxidant and antibacterial properties, showing significant antimicrobial activity against both Gram-positive (S. aureus) and Gram-negative (E. coli) bacteria, with minimum inhibitory concentration values of 0.62 mg/mL and 0.85 mg/mL, respectively. Mechanistic studies revealed that bacterial cell death likely results from strong electrostatic interactions between the negatively charged bacterial surfaces and the positively charged CDs.Conclusion: This work presents a cost-effective and eco-friendly approach to producing carbon dots with dual functionality as both antibacterial and antioxidant agents.

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