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Iodonium(III) Ylide: An Iodoalkylation Reagent with Aryne

Journal 2025 · IF 3.6 · 发表于 2025 年 2 月 5 日
作者: Weigang Xu,Pengfei Li,Yuerong Li,Zhangwen Kou,Kaiyu Li,Hengqi Li,Sajjad Ali,Junfeng Pan,Zhengshen Wang,Huaiji Zheng
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摘要

A tandem Hexadehydro-Diels–Alder (HDDA)/[2 + 2] cycloaddition/aryl migration reaction of iodonium ylide with tetrayne is described, in which iodonium ylide served as a unique double bond and reacted with aryne to form a four-membered iodonium(III) cycle, then converted to iodoarene after aryl group migration from iodine to adjacent carbon. This strategy allows the efficient construction of fully substituted iodoarene compounds.