已核实 DOI PubMed 相关产品: 27

3D-Printed Kirigami-Inspired Asymmetric Dressings: Custom Elasticity and Self-Pumping for Enhanced Wound Healing

Journal 2025 · IF 5.1 · 发表于 2025 年 4 月 11 日
作者: Zhen Gu,Siyang Cheng,Zhe Huang,Heng An,liping zhou,Yongqiang Wen
阅读全文 在 PubMed 查看

摘要

Preventing infections and managing excessive exudate in dynamic joints are vital for effective wound treatment. Accurately fitting dressings to wound shapes remains a significant challenge, which can adversely affect both healing and patient comfort. This study introduces a self-pumping dressing with tailored shape and tensile properties. This dressing channels excessive wound fluid in a unidirectional manner, achieved by electrospinning hydrophobic nanofibers embedded with silver nanoparticles (AgNPs) onto a hydrophilic 3D-printed patch featuring a kirigami structure. By systematically adjusting parameters-cutting length l, horizontal spacing d, and vertical spacing ℎ, we enabled the elongation of the 3D-printed patch to range from 26% to 244%. Our personalized self-pumping dressings demonstrated effective antibacterial activity, unidirectional fluid transmission, and biocompatibility, thereby accelerating wound healing. This research establishes a promising pathway for personalized and precise local wound care.

本研究中使用的阿拉丁产品

27 款产品在本文中被引用