Submicron spherical carbon modified boron-doped diamond for sensitive detection of sertraline hydrochloride

Boron-doped diamond (BDD) is suitable for use as an electrochemical analytical electrode for real-time detection because of its ultra-wide electrochemical potential window and low background current. However, the practical application of planar BDD electrodes is limited by their low conductivity, few active sites, and insufficient detection sensitivity, which need to be improved by surface modification. In this study, submicron carbon spheres (SMCS) were deposited on BDD substrate by a simple CVD method. The composite structure (SMCS/BDD) has a large specific surface area and high conductivity, which improves the sensitivity for drug detection. These results indicate that BDD-based all‑carbon materials have the potential to be used as electrodes for medical sensors.