Metal-organic framework UiO-66-NH2 functionalized polydopamine-modified magnetic multi-walled carbon nanotubes for convenient magnetic solid-phase extraction of sixteen quinolones

In this study, an innovative magnetic solid-phase extraction adsorbent based on metal-organic framework UiO-66-NH 2 functionalized polydopamine-modified magnetic multi-walled carbon nanotubes (Fe 3 O 4 @MWCNTs@PDA@UiO-66-NH 2 ) was developed for the selective extraction of trace amounts of quinolones (QNs) from milk and honey. Under optimal conditions, when coupled with ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS), the developed approach demonstrated excellent linearity in the concentration range of 0.1–100 μg kg −1 (R 2  ≥ 0.9916). The recoveries for sixteen QNs ranged from 72.4 % to 108.9 %, with relative standard deviations less than 9.40 %. The limits of detection were 0.012–0.450 μg kg −1 for milk and 0.023–0.690 μg kg −1 for honey. Finally, the method was successfully applied to the quantification of QNs in milk and honey samples.