Electrochemical Sensing of Acetaminophen Based on CuO/CNTs/g-C3N4 Composite

This study investigates the application of a copper oxide/carbon nanotubes/carbon nitride(CuO/CNTs/g-C3N4) composite as electrode material for acetaminophen detection. The synthesized nanomaterials were characterized using scanning electron microscopy, transmission electron microscopy, energy-dispersive spectroscopy, and powder X-ray diffraction. The electrochemical behavior of acetaminophen was assessed via cyclic voltammetry and square wave volammetry methods. The synergistic effects of CuO, g-C3N4 and CNTs enhance electron transfer, facilitating the conversion of irreversible oxidation processes into reversible redox events. The CuO/CNTs/g-C3N4 sensing electrode exhibited a significantly stronger redox peak signal, reflecting improved catalytic performance for acetaminophen detection. The sensor demonstrated a linear detection range of 0.02–0.1 and 1–120 μmol l−1, with a detection limit of 5.89 nmol l−1. The results affirm that the CuO/CNTs/g-C3N4 sensing electrode provides robust reproducibility and stability for the determination of acetaminophen.