Research on the mechanism of Polycyclic Aromatic Hydrocarbons interfering with the metabolism of taste substances in Ruditapes philippinarum

Polycyclic Aromatic Hydrocarbons (PAHs), as persistent organic pollutants widespread in marine environments, significantly impact ocean ecosystems. However, their effects on the taste quality of aquatic animals and the underlying mechanisms remain unknown. This study investigated the changes in content and metabolism of taste substances in Ruditapes philippinarum under PAHs stress. The results showed that PAHs reduced the umami and sweet tastes of R. philippinarum but enhanced its bitterness. In addition, the EUC value in soft tissue of R. philippinarum was significantly decreased by PAHs. The expression levels of key genes showed that PAHs mainly interfere with the mTOR signaling pathway, AMPK signaling pathway, and the synthesis and decomposition processes of taste substances, altering the content of taste substances in R. philippinarum and affecting their taste quality. This study will provide scientific warning and support for the quality assurance of aquatic products and the monitoring of marine PAHs pollution.