Hydroxylated Multi-Walled Carbon Nanotubes and Spherical Zn-MOF Nanoparticles Enable Electrochemical Detection of Trans-Resveratrol

Trans-resveratrol (TRA) has garnered significant attention due to its multiple pharmacological activities. This study fabricated a Zn-MOF/MWNTs-OH/GCE electrochemical detection platform for TRA detection by modifying a glassy carbon electrode (GCE) with a composite of hydroxyl-functionalized multi-walled carbon nanotubes (MWNTs-OH) and zinc-based metal-organic framework (Zn-MOF). The structure and composition of the materials were characterized using scanning electron microscopy, energy-dispersive X-ray spectroscopy, X-ray photoelectron spectroscopy, and X-ray diffraction. The results indicate that the Zn-MOF/MWNTs-OH/GCE has an excellent electrochemical response to TRA, featuring a linear detection range of 1.00- 600.00 μM and a detection limit of 0.32 μM. Additionally, the detection platform exhibits good reproducibility, stability, and selectivity. In the grape skin sample detection, the recovery rate ranges from 98.48% to 105.19%, the RSD is less than 4.62%, and the accuracy of the results is verified by fluorometry.